The viral envelope glycoproteins involved in receptor binding that determine viral tropism are reviewed, and mechanisms of viral dissemination explained. Cell polarity influences viral exit from ...

The Trofile coreceptor tropism assay is commercially available to detect the presence of CCR5, CXCR4, or dual- or mixed-tropic virus. The tropism assay can detect CXCR4-tropic virus nearly 100% of ...