Atherogenic lipoprotein particles can vary considerably in their cholesterol content, but each particle contains only one molecule of apoB-100 (or simply apoB). As a result, serum concentration of ...

Knockdown of ApoB, the protein required to produce VLDLs and LDLs, by antisense oligonucleotides is another approach for blocking the efflux of lipids from the liver. Studies in animal models and ...