IN a recent paper, D. E. Green 1 published values of the potentials of the systems hypoxanthine &rlharr; uric acid, xanthine &rlharr; uric acid, which I had already determined 2.

For gout, xanthine oxidase (XO) inhibitors are the choice for first-line urate-lowering therapy (ULT) according to the 2020 American College of Rheumatology Guideline for the Management of Gout ...

[23] Xanthine oxidase inhibitors block uric acid production, as xanthine oxidase catalyzes the oxidation of hypoxanthine to xanthine and xanthine to uric acid. Allopurinol has become the most ...