Explore a cfDNA library preparation workflow that provides high yield and conversion to improve sensitivity and detection of low variant allele frequencies (VAF). Cell-free DNA (cfDNA) contains ...
The Twist cfDNA Library Preparation Kit addresses challenges associated with library preparation from circulating cell-free DNA (cfDNA). Liquid biopsies have gained prominence in oncology research, ...
Karius has developed a cell-free-DNA-based diagnostic test capable of identifying bacteria, mycobacteria, DNA viruses, fungi and protozoa in the blood down to the species level, thereby rapidly ...
As shown in Figure 1, once the sample is received and accessioned at Karius, the cfDNA is isolated and a sequencing library is prepared. Next, the amplified, tagged sample is sequenced and ...
In 107 patients, 48.6% of those who received unusual or nonreportable clinical cfDNA-sequencing results had an occult cancer, reported Diana W. Bianchi, MD, of the Eunice Kennedy Shriver National ...