Explore a cfDNA library preparation workflow that provides high yield and conversion to improve sensitivity and detection of low variant allele frequencies (VAF). Cell-free DNA (cfDNA) contains ...
The Twist cfDNA Library Preparation Kit addresses challenges associated with library preparation from circulating cell-free DNA (cfDNA). Liquid biopsies have gained prominence in oncology research, ...
Twist泛癌种cfDNA参照标准品包含大量多样化的变异供研究使用。该参照标准品通过准确合成变异并精确控制特定的变异等位基因频率(VAF)来生成,很好地模拟了游离DNA和循环肿瘤DNA的大小分布和片段化图谱,能够推动更高性能分析的开发。 该参照标准品包含了 ...
Karius has developed a cell-free-DNA-based diagnostic test capable of identifying bacteria, mycobacteria, DNA viruses, fungi and protozoa in the blood down to the species level, thereby rapidly ...
As shown in Figure 1, once the sample is received and accessioned at Karius, the cfDNA is isolated and a sequencing library is prepared. Next, the amplified, tagged sample is sequenced and ...
In 107 patients, 48.6% of those who received unusual or nonreportable clinical cfDNA-sequencing results had an occult cancer, reported Diana W. Bianchi, MD, of the Eunice Kennedy Shriver National ...