They then used CRISPR-Cas9 to eliminate the target gene and create EGFR knockouts. A western blot of protein extracted from these knockout cells showed that there was no longer any signal for a ...
EGFR mutations are present in 10 to 15 percent of Western patients with NSCLC with adenocarcinoma histology and occur in 40 to 50 percent of Asian patients. EGFR ex19del or EGFR exon 21 L858R ...