eIF4F由三个亚基组成：负责直接结合帽端的eIF4E、具有解旋酶功能的eIF4A以及作为支架蛋白的eIF4G。这些亚基共同协作，帮助将mRNA招募到核糖体预起始 ...

The cap was found to have a crucial role in mRNA translation, and eukaryotic translation initiation factor 4E (EIF4E) was the first protein identified to bind directly to the cap to recruit ...