A new study reveals that certain diets, particularly those high in fat and sugar, could significantly increase the risk of ...

The six subunit ORC is essential for initiation of DNA replication in eukaryotes. Cancer cell-lines in culture can survive and replicate DNA replication after genetic inactivation of individual ORC ...

as cell membrane stabilisers and permeability regulators that prevent hepatotoxic agents from entering hepatocytes; (iii) as promoters of ribosomal RNAsynthesis, stimulating liver regeneration ...

The accumulation of lipids in hepatocytes in nonalcoholic fatty liver disease (NAFLD) leads to an increase in reactive oxygen species and changes in the intracellular microenvironment, while ...

Pyruvate occupies a central node in carbohydrate metabolism such that how it is produced and consumed can optimize a cell for energy production or biosynthetic capacity. This has been primarily ...