单碱基m6A位点的意义：总结了单碱基m6A位点的功能意义。 miRNA的非经典功能 tsRNA(tRF&tiRNA) tRNA miRNA最常被提到的作用机制是通过RISC复合体靶向降解mRNA，同时其他的lncRNA、circRNA分子也可以通过竞争性结合miRNA，发挥ceRNA机制。此部分则通过多个不同的案例总结了miRNA ...

这些方法是模棱两可的，尤其是对于低丰度的修饰：即使你有一个高纯度的 mRNA 制剂，你还是担心微量的污染转移 RNA (tRNA) 或核糖体 RNA (rRNA) 可能是修饰的来源。这使得很难确定修饰的核苷酸是否来自 mRNA。” 从目前的研究成果来看，表观转录组影响深远 ...

The process of translation can be seen as the decoding of instructions for making proteins, involving mRNA in transcription as well as tRNA. But where does translation take place within a cell?

During translation, the ribosome moves along the mRNA, and as it does this, a different type of RNA called a tRNA gets involved. Different tRNAs have different three-base "anticodons" on one end ...

An often-overlooked mechanism of gene regulation may be involved in the failure of antifungal drugs in the clinic, claims a ...

Researchers from the Leibniz Institute for Natural Product Research and Infection Biology discovered that RNA modifications ...

tRNAs have a distinct cloverleaf secondary structure and an L-shaped tertiary structure. The cloverleaf structure is formed by the folding of the single-stranded tRNA molecule, which is typically ...

The mRNA then travels to the ribosome, where translation occurs ... allowing for more flexibility in codon recognition. Wobble base pairing enables a single tRNA molecule to recognize multiple codons ...

RNA breaks destined for repair are inflicted by sequence-specific or structure-specific endoribonucleases during physiological RNA processing (e.g. tRNA splicing; kinetoplast mRNA editing) and under ...

When a gene is to be expressed, the base sequence of DNA is copied or transcribed into mRNA (messenger RNA). This process takes place in the nucleus and occurs in a series of stages. The two ...