Monoamine oxidase inhibitors (MAOIs) were the first medications approved for the treatment of depression symptoms and are also used to treat several other medical conditions, such as Parkinson's ...

Summary: Rasagiline is a novel, investigational propargylamine that irreversibly and selectively inhibits monoamine oxidase type B (MAO-B). Rasagiline demonstrates complete and selective ...

a MAO-B = monoamine oxidase type B, MAO-A = monoamine oxidase type A. b Expressed as the molar concentration of drug required to inhibit enzyme activity by 50% (nmol/L). c Expressed as the ...