Neonatal alloimmune neutropenia is due to maternal production of antibodies directed against neutrophil specific antigens (NA1, NA2, NB1, NC1) reacting with fetal-neonatal and paternal neutrophils.
X4 to receive a €28.5 million upfront payment and up to €226 million in potential regulatory and commercial milestone payments in addition to tiered, double-digit royalties up to the mid-twenties ...
The condition can increase the risk of infections. Neutropenia or low levels of neutrophils, primarily results from chemotherapy. It could also result from conditions that disrupt normal ...
Late-onset neutropenia (LON) is emerging as a common adverse effect to rituximab therapy owing to widespread use of this drug in the treatment of B-cell lymphomas and autoimmune diseases.
Objective: To systematically evaluate the literature to determine whether vancomycin-induced neutropenia is dose- or duration-related and provide clinicians with feasible treatment alternatives.
X4 to receive a €28.5 million upfront payment and up to €226 million in potential regulatory and commercial milestone payments in addition to tiered ...
PRT2527 demonstrated a manageable safety profile with most common side effects being neutropenia (48%) and nausea (33%). No treatment-emergent adverse events (TEAEs) led to discontinuation in the ...