This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when ...
New catheter materials for peripherally inserted central catheters (PICCs) may reduce the risk of device failure due to infectious, thrombotic, and catheter occlusion events. However, data from ...
Allogeneic hematopoietic stem-cell transplantation is the only curative treatment for myelofibrosis. Driver mutations are the pathophysiological hallmark of the disease, but the role of mutation ...
Talquetamab is a T-cell–redirecting bispecific antibody targeting G protein–coupled receptor class C group 5 member D (GPRC5D). 13-15 In the MonumenTAL-1 study, more than 71% of the patients ...
Multiple diseases in children have been linked to manufactured synthetic chemicals, which are subject to few legal or policy constraints. A revamping of law and restructuring of the chemical ...
The Race and Medicine collection reflects NEJM’s commitment to understanding and combating racism as a public health and human rights crisis. Our commitment to antiracism includes efforts to ...
For over 200 years, the New England Journal of Medicine (NEJM) has brought important medical news to the world’s most influential physicians. The global medical community, physicians, and ...
This is a retrospective study of the history, roentgenology and autopsy pathology when appropriate of all infants with severe respiratory-distress syndrome who required twenty-four hours or more ...
What left ventricular ejection fraction (LVEF) range is a component of the contemporary definition of heart failure with preserved ejection fraction? The current nomenclature defines heart failure ...