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重塑免疫抑制微环境!兰州大学发文:揭示胃癌治疗新策略
【导读】肿瘤相关巨噬细胞(TAMs),尤其是 M2 极化的 TAMs,在胃癌(GC)的进展、免疫逃逸和治疗耐药中起着重要作用。尽管针对 TAM 招募或耗竭的靶向治疗已有所尝试,但临床疗效仍有限。因此,寻找能够特异性抑制或重编程 M2 极化 TAMs ...
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