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创新技术突破药物筛选困境!癌症靶点有望迎来选择性抑制剂
▎药明康德内容团队编辑 编者按:血红素加氧酶1(HO-1)是癌症治疗的新兴靶点,这种酶的高表达与多种癌症的进展相关。不过,由于HO-1和同家族HO-2的序列相似性,选择性HO-1抑制剂的开发极具挑战性。现在,DNA编码化合物库(DEL)为苗头化合物的 ...
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