Bile acids (BAs), traditionally recognized for their role in dietary fat digestion and cholesterol metabolism, are increasingly implicated as key regulators in obesity-related diseases (1). Beyond ...

A team of scientists in China said they have discovered how a type of bile known as lithocholic acid (LCA) can slow down ageing in a way similar to how calorie restriction or fasting work.

Palmitic acid is a saturated long-chain fatty acid (LCFA), a term for fatty acids containing 13 to 21 carbons. Palmitic acid contains 16 carbons. This acid is found in most fats and oils ...

This may be because omega-3 polyunsaturated fatty acids may help protect against the development of gallstones. Protein is essential for the repair and growth of body tissues. Red meat and dairy ...

Read the paper: Lithocholic acid binds TULP3 to activate sirtuins and AMPK to slow down ageing Generally speaking, bile is less interesting than is longevity, but that might soon change.

In a paper in Nature, researchers at the Chinese Academy of Sciences and Xiamen University report that they have identified one such caloric restriction mimetic—a bile acid called lithocholic ...

Gallbladder blockages, such as gallstones, can cause severe pain and illness. Other gallbladder problems include bile duct infection and gallbladder cancer. They often require urgent medical ...

The content of tartaric acid in the finished wine not to be less than 1,500 ppm weight by volume. n/a (d) Grape juice (d) Acidity regulator (d) Good Manufacturing Practice n/a (e) Ice cream mix; Ice ...

Microbes living in our guts help us digest food by reshaping the bile acids that our livers produce for breaking down fats. It turns out that two of these microbially-modified bile acids may ...

The dichotomous roles of microbial-modified bile acids 7-oxo-DCA and isoDCA in intestinal tumorigenesis. Proceedings of the National Academy of Sciences , 2024; 121 (47) DOI: 10.1073/pnas ...