Hexoprenaline proved to be the most chronotropically beta2-selective drug, having the least effect on the beta1-adrenoreceptors of the heart, for an equivalent effect on the uterus. Blood pressure ...

While β3-adrenoreceptors remain inactive under basal conditions, they can induce negative inotropic effects during intense adrenergic stimulation and mediate processes like lipolysis and thermogenesis ...

Objective: To compare the haemodynamic effects of nebivolol, a highly selective antagonist of 1-adrenergic receptors with additional actions caused via the L-arginine/nitric oxide pathway, with ...

Shenzhen Key Laboratory of Systems Medicine for inflammatory diseases, School of Medicine, Shenzhen Campus of Sun Yat-Sen University, Sun Yat-Sen University, China; Department of Cardiovascular ...

Objectives Takotsubo stress cardiomyopathy (TSC) is an increasingly recognised and diagnosed disease, although the underlying pathophysiology is still unknown. Our aim was to investigate the effect of ...

The study identifies the adhesion G-protein-coupled receptor A3 (ADGRA3) as a potential target for activating adaptive thermogenesis in white and brown adipose tissue, providing valuable information ...

β-adrenergic receptors (β-ARs) play a critical role in modulating learning, memory, emotionality, and long-term synaptic plasticity. Recent studies indicate that β-ARs are necessary for long-term ...

Faculty of Pharmacy and Research and Innovation Hub, Alamein International University, Alamein, Matrouh 51718, Egypt Department of Pharmacology and Toxicology, Faculty of Pharmacy, Alexandria ...