Results of a prospective, randomized, controlled trial indicate that allopurinol lowers serum uric acid levels and reduces the rate of renal degeneration in patients with mild to moderate chronic ...

One regimen to consider for those commencing allopurinol at an early stage of gout presentation in a patient with normal renal function is to wait 3 weeks after an acute attack resolves ...

The patient was intolerant to allopurinol and had mild renal insufficiency ... and renal impairment with creatinine clearance of 29 ml/min (normal range 80–120 ml/min). The 24 h uric acid ...