Background Alveolar macrophages (AM) in COPD have fundamentally impaired responsiveness to Toll-like receptor 2 (TLR2) and TLR4 ligands of non-typeable Haemophilus influenzae (NTHI). However, the ...

Abstract Background: Idiopathic pulmonary alveolar proteinosis (PAP) has recently been recognised as a disease of impaired alveolar macrophage function caused by neutralising ...

MRL/lpr mouse treated with pristane + rMDA5 protein showed more alveolar macrophages that had lymphocyte infiltrations. After the alveolar hemorrhage by pritane, the antigen exposure of MDA5 might ...

while birefringent crystalline particles within the alveolar macrophages on polarized light microscopy indicate exposure to crystalline silicates. Quantitative assessment of the proliferative ...

Monocytes and macrophages are myeloid cells that have important innate immune functions. Macrophages reside in tissues and respond to infection by producing inflammatory mediators and engulfing ...

间质性肺疾病（Interstitial lung diseases，ILDs）是多样而复杂的，诊断和治疗通常有一定挑战，临床上有时对少（罕）见的ILD会识别和诊断不足。本文整理了肺泡蛋白沉积症（pulmonary alveolar ...

Antibiotic treatment during an influenza infection actually impaired the body’s efforts to clear bacteria rather than helping the body heal.

A contribution for AIM2 in NETS detection was reported in a lipopolysaccharide (LPS)-induced acute respiratory distress syndrome (ARDS) model during which intracellular NET-DNA binds the AIM2 receptor ...

These pathways might alter phenotypes of ATII cells in COPD lungs. Chronic obstructive pulmonary disease (COPD) is a major cause of chronic morbidity and mortality throughout the world and is ...

Researchers have discovered that aspartate plays a key role in making the lungs a common site for cancer metastasis.

Fatty acid synthase, the enzyme responsible for fatty acid production in cells, may be a therapeutic target for IPF, a mouse ...