Immunization with an amyloid β-peptide fragment reduces learning and memory impairments in mice, and this approach may eventually be used to prevent and/or treat this disease in people.
More than six million Americans are affected by Alzheimer’s disease, a form of dementia marked by accumulation of amyloid-β within the brain. Amyloid-β is a relatively small protein that forms ...
They explored the role of βHB in regulating the solubility of unstable and misfolded proteins, specifically neurodegeneration-related proteins such as amyloid-β, across various models.