Emerging evidence supports the argument that psoriatic arthritis arises from two pathways and that affected immune cells may ...

Viruses can serve as triggers of autoimmune disease by acting as adjuvants, leading to the priming of autoantigen-specific lymphocytes. Autoantigen-reactive T and B cells can also be activated ...

COUR Pharmaceuticals, a clinical-stage biotechnology company developing first-in-class, disease-modifying therapies designed ...

From the Department of Cardiology and Angiology I, University Heart Center Freiburg, Germany (D.W.) Faculty of Medicine, University of Freiburg, Germany (D.W.) K. Ley has received research funding for ...

DCs were loaded during the final 24 h of culture with the recall protein antigen, purified protein derivative (PPD; 1 µg/ml; Statens Serum Institut, Copenhagen, Denmark), or candidate RA autoantigen ...

诊断方面，2022年国际AIH小组发表的新共识将汇管区炎症和小叶内炎症均作为AIH的病理特征，强调了病理组织学在AIH诊断中不可或缺的地位。2024年一项回顾性研究提出，相较于应用广泛的2008年简化标准中的AIH病理评分，2022年IAHPG病理评分可能具有更高的诊断敏感性，特别是对于急性起病的AIH [1]。

1 Amgen R&D Postdoctoral Fellows Program, Amgen Inc, South San Francisco, CA, United States 2 Amgen Research, Amgen Inc., South San Francisco, CA, United States Tolerogenic vaccines represent a ...

Division of Rheumatology and Clinical Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA Dr R G Cooper, Rheumatic Diseases Centre, Hope Hospital, Salford, M6 8HD, UK; ...