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The EMBO Journal
1 天
Acidic pH can attenuate immune killing through inactivation of perforin
Perforin forms transmembrane pores in the plasma membrane, allowing granzymes to enter the target cell cytosol and trigger ...
2 天
EsoBiotec Doses First Patient in Investigator Initiated Trial of In Vivo BCMA CAR-T ...
Initial clinical observations suggest high level of T cells reprogramming and CAR-T expansion at the starting dose without lymphodepletion At 28 ...
3 天
The shot that keeps disease away
Concentrated efforts on the part of our government and WHO have completely eradicated smallpox and reduced the incidence of ...
BMJ
5 天
Immune checkpoint inhibitor-induced inflammatory arthritis persists after immunotherapy ...
Conclusion ICI-induced IA can become a long-term disease necessitating management by rheumatology for immunomodulatory treatment. Importantly, the use of immunomodulatory treatment has not been shown ...
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