For the first time in Nepal, genetic testing, also known as "Gene Sequencing," related to breast cancer (BRCA1 and BRCA2) has ...

The National Institute for Health and Care Excellence (NICE) has given a positive recommendation for Lynparza (olaparib) for ...

The DNA damage response is a network of cellular pathways that sense, signal and repair DNA lesions. Surveillance proteins that monitor DNA integrity can activate cell cycle checkpoints and DNA ...

Olaparib improved invasive disease-free survival, distant disease-free survival, and overall survival in high-risk ...

According to a new advisory from the U.S. Surgeon General, alcohol ranks as the third leading preventable cause of cancer in ...

Jan. 7, 2025 — A newly described dinosaur whose fossils were recently uncovered is challenging the existing narrative, with evidence that the reptiles were present in the northern hemisphere ...

Aberrant DNA repair machinery, another prominent feature of hot tumours, and the resulting genomic instability are predictors of susceptibility to PD-1/PD-L1 blockade therapy (Chen et al, 2022).

Many people are familiar with the BRCA1 and BRCA2 mutations which predispose to breast cancer. These genes are referred to as tumor suppressor genes which code for proteins that control the repair of ...

With so many at-home DNA tests now available to consumers, learning more about your ancestry is easier than ever. Plus, these tests make for thoughtful, unique holiday gifts. All you have to do is ...

Moderate penetrance genes, which increase the risk for breast cancer by twofold, include genes involved in DNA repair such as ATM, BRIP1 (BACH1), CHEK2, and PALB2. Still other genes are considered to ...