Meloxicam is an enolcarboxamide with preferential COX-2 activity. Studies conducted on experimental models and human tissues indicate that meloxicam is a more potent inhibitor of COX-2 than COX-1 ...

An interleukin-1β-mediated induction of COX-2 in the central nervous system contributes to inflammatory pain hypersensitivity. Nature 410 , 471–475 (2001). Article CAS Google Scholar ...

Meloxicam reaches maximum plasma concentration (Cmax) at 9-11 hours after a 30mg dose and 2.5-7 hours after a 15mg dose. Meloxicam is strongly bound to plasma proteins (99.5%). Meloxicam displays ...

COX-2 selective inhibitors belong to the family of nonsteroidal anti-inflammatory drugs (NSAIDs). NSAIDs reduce pain, fever and inflammation, but many can also lead to gastric bleeding ...

With the flu outbreak peaking, foods like ginger, bellflower, mackerel, kiwi, banana, and yogurt can help prevent and ...

Prostaglandins are chemicals in the body that promote inflammation, pain, and fever. COX-1 protects the stomach lining and ...

NSAIDs-- or nonsteroidal anti-inflammatory drugs -- are among the ... They block the effects of special enzymes -- specifically Cox-1 and Cox-2 enzymes. These enzymes play a key role in making ...

The development of safer and more effective anti-inflammatory drugs also presents vibrant opportunities. However, the market faces substantial challenges, such as stringent regulatory policies and the ...

Hunnes says that betalain has anti-inflammatory properties because it can suppress the cyclooxygenase-2 (COX-2) enzyme which is associated with inflammation. Chronic inflammation can cause damage ...