The core components of CRISPR-based genome-editing therapies are bacterial proteins called nucleases that can stimulate ...

麻省理工学院Broad研究所、哈佛大学和赛勒斯生物技术公司的研究人员现在已经设计了两种CRISPR核酸酶，Cas9和Cas12，以掩盖它们对免疫系统的影响。该团队确定了每个核酸酶上触发免疫系统的蛋白质序列，并使用计算建模来设计逃避免疫识别的新版本。与小鼠的标准核酸酶相比，工程酶具有相似的基因编辑效率和降低的免疫反应。

Professor Kevin J. Zwezdaryk and Chandler H. Monk discuss CRISPR and diagnostics, focusing on the development of a portable ...

据美国防创新委员会（DIB）1月8日消息，DIB连续发布《无人武器系统的扩展之路》《扩大非传统国防创新》两份报告。《无人武器系统的扩展之路》指出美国在大规模部署无人武器系统时正面临需求不明确、供应链漏洞等问题，并针对性提出优化需求信号、资金机制、部门架构和流程、供应链、制造和采购方面的建议。《扩大非传统国防创新》则指出，为提高国防采购系统对失败的风险承受能力，建议新国防部长和副部长应开放各军种采购 ...

A pipeline for the analysis of CRISPR edited data. It allows the evaluation of the quality of gene editing experiments using targeted next generation sequencing (NGS) data (`targeted`) as well as the ...

The integration of artificial intelligence (AI) in the biotech industry seems boundless. Its combination with CRISPR could be the one area where AI has the most potential. Nobel prize winner and ...

凭借强大的创新能力，瑞风生物已在基因编辑药物研发方面取得了多项世界领先的成果。目前，瑞风生物是全球唯一实现治愈α和β两类地中海贫血遗传病的创新科技公司。地中海贫血全球受累人群广泛，存在重大未被满足的临床需求。瑞风生物先导产品β-地中海贫血RM-001 ...

Peter Mac scientists have found a way to use the powerful gene editing tool CRISPR to silence cancer-causing gene mutations which, up to now, have remained off-limits to targeted drugs. Dr.