Sustained exposure to pathological stress stimulates the heart to hypertrophy, increasing disease and mortality risk. New therapies to blunt this process include targeting enzymes below the cell ...

Aim Differentiating physiological cardiac hypertrophy from pathology is challenging when the athlete presents with extreme anthropometry. While upper normal limits exist for maximal left ventricular ...

Another active area of research in the laboratory focuses on unraveling the mechanisms behind maladaptive, or pathological, and adaptive, or physiological, cardiac hypertrophy. In response to certain ...

Heart failure is the terminal stage of various cardiovascular diseases, usually characterized by pathological myocardial ...

A study reveals that a personalized approach, considering age, sex and size, improves the diagnosis of hypertrophic ...

Left ventricular hypertrophy (LVH) is an abnormal thickening of the left ventricular myocardium that occurs as an adaptive mechanism to increased afterload. The left ventricular myocytes ...

Right ventricular hypertrophy occurs when the right ventricular wall thickens due to chronic pressure overload, similar to that of left ventricular hypertrophy. RVH is diagnosed on ECG in the ...

More information: Xiang Nie et al, lncRNA ZNF593-AS inhibits cardiac hypertrophy and myocardial remodeling by upregulating ...

Background and aims Hypertrophic cardiomyopathy (HCM) has various aetiologies, including genetic conditions like Fabry ...

Cardiovascular system Cardiac hypertrophy; increased stroke volume (SV) at rest and during exercise; decrease in resting heart rate (HR); increase in cardiac output (Q); capillarisation at the ...