CRISPR-Cas9 genome editing exploits the CRISPR-Cas system to modify a genome in a targeted manner. Guided by RNA, the Cas9 endonuclease breaks DNA at a target sequence. Imprecise repair of the ...

引言视力是人类感知世界的主要途径之一，但各种视网膜疾病正威胁着数百万人的生活质量。在这些疾病中，Stargardt ...

Using Cas9, the authors restored dysferlin in muscle stem cells from patients ex vivo and show proof-of-concept for autologous cell replacement therapies in a new humanized mouse model.

Impact and progress Frontiers' impact Progress Report 2022 All progress reports ...