AAVs are used to deliver gene editing tools such as CRISPR-based adenine base editors (ABEs). A Cas9 nickase is fused to an evolved adenosine deaminase to convert adenine nucleotides to guanine ...

引言视力是人类感知世界的主要途径之一，但各种视网膜疾病正威胁着数百万人的生活质量。在这些疾病中，Stargardt ...

Our study examined the mutation efficiency of the CRISPR/Cas9 method for tryptophan aminotransferase BnaTAA1 genes involved in the auxin biosynthesis pathway. We made nine CRISPR/Cas9 constructs with ...

HIPS是亥姆霍兹感染研究中心（HZI）与萨尔大学合作的一个站点。 ACTIMOT是“Advanced Cas9-mediaTed In vivo MObilization and mulTiplication of BGCs”的缩写，它利用CRISPR-Cas9技术，该技术被称为“基因剪刀”，因此可以对细菌的遗传物质进行精确干预。由于生物合成基因簇在实验 ...

Key Laboratory of Biorheological Science and Technology, Ministry of Education and Bioengineering College, Chongqing University, Chongqing 400044, China ...