the 17-h dipyridyl treatment of the COS-7 cells increased HIF-1α binding by more than threefold. The microassay plate-based NoShift Assay offers several advantages over traditional gel shift assays.

Cellular immunogenicity and immunotoxicity assays help scientists design, validate, and translate therapeutic research into treatments that weaponize the immune response against cancer.

And the role of flow cytometry? “It is how you identify the cells that will go in the product,” says Therese Choquette, head of analytical sciences at Switzerland-based Tigen Pharma.

CAR-T cell products’ quality control standards incorporate characterization, uniformity, and purity testing to ensure and ...

Pellet 106 cells by centrifugation (250 - 300 x g) and carefully remove supernatant Make up 1X of fixation buffer by adding 5 ml of Cytofix (BD554655) to 10 ml of DPBS Add either 300μl (for microwell ...

It can precisely select single cells on a chip, carry out several single-cell assays, and export target cells based on particular ... are organized by flow cytometry. What is the maximum number ...

For example, researchers will measure cell death to determine a drug’s anticancer effectiveness. Scientists commonly use caspase assays to evaluate apoptosis, evaluating caspase activation—a hallmark ...

Discover how targeting RNA-binding motif protein 39 (RBM39) is unlocking new possibilities in cancer treatment ... technology to quantify RBM39 degradation in neuroblastoma (SH-SY5Y) cancer cells.

flow-based tests can quickly deliver reliable results in challenging settings. When designing a new test and designing out a component in an existing test-what are the key considerations and what will ...

The findings are significant for the liver research community and others interested in the gut-liver axis. (A) AOAH cleaves the two piggyback fatty acyl chains from the lipid A moiety, inactivating ...

Calcineurin fine tunes the balance between proliferation and differentiation of Notch-responsive progenitors in the pancreatic ducts to enable beta cell regeneration in zebrafish.

No industry or technology is perfect, certainly not new ones like cell-cultured and plant-based meat. Scandals and corporate subterfuge ought to be reported on whenever they arise, but journalism ...