Chromatin Bioscience is pleased to announce its ongoing collaboration with EsoBiotec, which has successfully advanced its ESO-T01 in vivo CAR-T candidate into clinical trials. ESO-T01 is the first in ...

Short-chain fatty acids influence gene regulation and chromatin accessibility, highlighting their role in colorectal cancer ...

The following is a summary of “FC03 T17 polarization of skin-homing (CLA-positive) T cells is maintained by ...

In contrast to this approach, Fu et al. developed a model that is trained directly on chromatin-accessibility data from diverse cell types (Fig. 1). In this way, a single unified model can learn ...

Chromatin is a flexibly joined chain of nucleosomes that exists inside the nucleus of eukaryotic cells and has been described as a 'bead on a string'. Chromatin organization strengthens DNA for ...

First-in-class oral selective SMARCA2 (BRM) inhibitor, FHD-909 (LY4050784), advancing in Phase 1 trial for SMARCA4 mutated cancers, with ...

In a groundbreaking study, scientists have discovered a way to manipulate the very fabric of life by using light to reshape ...

Select the journal/section where you want your idea to be submitted: The regulation of gene expression in eukaryotes is controlled by many factors, among which the composition and spatial organization ...

【导读】胰岛素样生长因子 2（IGF2）和 H19 在肝细胞癌（HCC）中过度表达。IGF2 衍生的 miR-483-5p 与癌症的发展有关。在此，研究人员研究了 miR-483-5p 在 IGF2 和 H19 ...

New research from the Center for Physical Genomics and Engineering uncovers how 3D genome structures generate cellular memories, paving the way for advances in medicine and longevity through cellular ...

Centromeres play a crucial role in cell division, with CENH3 guiding retrotransposon Tal1 integration, revealing insights ...

We have publicly presented scCASdb, a standardized, high-quality, and user-friendly database for studying single-cell chromatin accessibility and gene regulation across a wide range of species, organs ...