A number of comparative studies have been performed with metoprolol, a β 1-selective "second-generation" β blocker, and carvedilol, a nonselective and vasodilatative "third-generation" β blocker.

Maack et al. [70] recently reported on switching between β blockers (metoprolol and carvedilol) in 68 patients treated with either agent for 1 year who had improved in terms of LVEF and NYHA class.

The classification of drugs have been around since 1964 after Sir James Black discovered how they can assist people with ...

Carvedilol is a generic drug that’s prescribed for high blood pressure and other heart conditions in adults. As with other drugs, carvedilol can cause side effects, such as low blood pressure ...

By contrast, a recent randomized, controlled trial shows less bleeding associated with the use of carvedilol compared with EBL. Portal hypertension is a life-threatening complication of cirrhosis ...

Beta blockers are frequently mentioned in the news, such as when Los Angeles Chargers Head Coach Jim Harbaugh disclosed his battle with heart disease in October. A significant number of Americans, ...

Hypertension, also known as high blood pressure, is the most common cardiovascular risk factor. It describes a condition ...

Professor Poole-Wilson, Professor Coats and Dr Flather at Imperial and the Royal Brompton Hospital designed and led pioneering randomised clinical trials which defined the use of these agents in heart ...

In addition to blocking the receptor sites for catecholamines, third-generation β-blockers with associated vasodilating properties, such as carvedilol and nebivolol, provide a broad spectrum of ...