The project aims to create a morphological atlas of microbial eukaryotes, integrating phenotypic data with genomic and ...

Conclusion: We characterize the homeodomain transcription factor EN1 as a molecular amplifier of TGFβ signaling in myofibroblast differentiation that coordinates cytoskeletal organization in a ...

The cytoskeleton of eukaryotic cells is made of filamentous proteins, and it provides mechanical support to the cell and its cytoplasmic constituents. All cytoskeletons consist of three major ...

An international team of scientists led by Université de Montréal medical professor Frédéric Charron, director of the ...

This important study leverages the power of Drosophila genetics and sparsely-labeled neurons to propose a new model for neuronal injury signaling. The authors present convincing evidence to support ...

In his memory, the Peter Frates Family Foundation will be hosting another 'Plunge4Pete' on that day at Good Harbor Beach in ...

In human lung fibroblasts, Ca2+ flickers arise from both TRPM7 Ca2+ influx, sensing mechanical signals, and IP3R Ca2+ release ...

eLife is a non-profit organisation inspired by research funders and led by scientists. Our mission is to help scientists accelerate discovery by operating a platform for research communication that ...

The late, great Pete Frates would’ve turned 40 years old on Saturday, Dec. 28. In his memory, the Peter Frates Family ...

Proteins are biopolymers of amino acids (polypeptides), joined by peptide bonds, that are generated by ribosomes. The amino acid sequence, encoded by its gene, determines a protein’s structure ...