Key Laboratory of Luminescence Analysis and Molecular Sensing (Southwest University), Ministry of Education, Institute of Developmental Biology and Regenerative Medicine, College of Chemistry and ...

Covalent modification of the oncogene product Mdm2 by the ubiquitin-related protein SUMO1 protects it from ubiquitination and enhances its E3 ligase activity ... for DNA-damage-induced ...

This process is essential for DNA replication ... indicates that this function of Cks1 is independent of CDKs and links Cks1 with the Skp2 subunit of the SCF ubiquitin ligase.

SAN FRANCISCO, Jan. 06, 2025 (GLOBE NEWSWIRE) -- (Nasdaq: NRIX), a clinical stage biopharmaceutical company developing ...

Jan. 8, 2025 — Researchers have unearthed two fossils, named Punk and Emo, revealing that ancient molluscs were more complex and adaptable than previously ...

With so many at-home DNA tests now available to consumers, learning more about your ancestry is easier than ever. Plus, these tests make for thoughtful, unique holiday gifts. All you have to do is ...

Shelby Brown (she/her/hers) is an editor for CNET's services team. She covers tips and tricks for apps, operating systems and devices, as well as mobile gaming and Apple Arcade news. Shelby also ...

while the ubiquitin ligase Siah2 prevents premature migration by degrading essential proteins. Researchers have identified genetic variations in brain cells, particularly microglia and ...

The ensuing study, published in Nature Communications on October 26, 2024, reveals a delicate "Goldilocks" zone -- a specific magnesium concentration range -- where DNA wraps around polyP ...

They identified a "push-pull" system where the guidance molecule Netrin-1 repels differentiated neurons, while the ubiquitin ligase Siah2 prevents premature migration by degrading ... Researchers ...

Scientists have long agreed that early humans mated with Neanderthals, but a pair of recent studies have shed light on when exactly this DNA mixing occurred. Such a revelation could help ...