Tufts Center for the Study of Drug Development (Boston ... Each heavy chain is attached to a light chain by disulfide bonds, and the two heavy chains are likewise attached by a third disulfide ...
A study with the DNA tumour virus SV40 now shows that protein folding and quality-control factors of the endoplasmic reticulum reshuffle disulfide bonds within ... of anti-viral drugs ...
disrupting disulfide bond formation. Additionally, they showed that the proposed reporter can detect defects in protein translocation induced by a potential anti-HIV drug, signaling the successful ...