During transcription, newly minted RNA sticks to its DNA template, forming a 3-stranded structure known as an R-loop. While ...

How do bacteria, lacking a nucleus, organize and pack their genome into the cell ... particularly with regard to chromosomal structure and organization. Supercoiling explains how chromosomes ...

Researchers at Rockefeller University have discovered a new mechanism for maintaining genome stability in bacteria. This ...

At this point, the genome engineers' job became a bit like a railway engineer's maintenance programme - replacing the E. coli genome piecewise - section by section - rather than all at once.

From a genetic perspective, it is the worst-case scenario for a bacterium: during transcription, freshly created RNA adheres to its DNA template to form a three-stranded structure called an R-loop.