Comparison between the mean miRNA concentration and mean exosomal concentration between the lung adenocarcinoma patients and the control group revealed significant differences among these groups.

Finally, the potential role of EV-derived miRNAs as targets in the diagnosis and treatment of cardiac hypertrophy will be discussed. It is well known that miRNA-mediated transcriptional and ...

The researcher has given an overview on the regulatory network of extracellular circRNAs in cancer and their impact on cancer drug resistance. In order to propagate malignancy, circRNAs shuttle ...

撰文丨王聪编辑丨王多鱼排版丨水成文衰老（Aging）是一种内在的生物学过程，其特征是系统性变化逐渐损害生理完整性，并增加患年龄相关疾病的风险，最终导致死亡。衰老的标志包括细胞衰老、基因组不稳定、表观遗传改变、蛋白稳态丧失、干细胞耗竭、慢性炎症以及细胞 ...

传统观点认为，细胞衰老是一种不可逆的状态，与“细胞增殖极限”密切相关。然而，研究团队发现，细胞自然达到增殖极限并非是导致衰老的关键，真正促使衰老发生的原因是，氧化应激、DNA损伤等多种压力促使细胞提前进入了增殖阻滞状态。此时细胞并没有触及自然状态下的 ...

January 14, 2025 • Syria's new rulers faces one of their first serious challenges: bread lines. For Syrians, the long wait is a struggle — but for some, bread is a business opportunity.

▎药明康德内容团队编辑   20世纪60年代，美国细胞生物学家Leonard Hayflick在体外培养细胞时发现细胞分裂次数是有限的。当细胞培养到一定代数的时候，细胞会停止分裂进入一种增殖阻滞状态，这一界限也被称作Hayflick界限。

Obesity is associated with chronic, low-grade inflammation. Excessive nutrient intake causes adipose tissue expansion, which may in turn cause cellular stress that triggers infiltration of ...

Heidi Schwarzenbach的论文“Impact of exosomal and cell-free circRNAs on cancer drug resistant”发表在ExRNA杂志上，综述了多种靶向多种miRNA的circRNAs在耐药中的作用。 作者综述了细胞外环状RNA在癌症中的调控网络及其对癌症耐药的影响。为了传播恶性肿瘤，环状RNA作为无细胞分子 ...

总之，这篇关于circrna的简短综述代表了其临床应用的潜在优点和缺点。了解它们在未来的临床价值将是令人兴奋的。 Heidi Schwarzenbach的论文“Impact of exosomal and cell-free circRNAs on cancer drug resistant”发表在ExRNA杂志上，综述了多种靶向多种mirna的circRNAs在耐药中的作用。