Individuals with early-onset COPD and rapidly progressive pre-COPD frequently have a decades-long history of impaired ...

Preserved ratio impaired spirometry (PRISm) is associated with an increased mortality risk, researchers reported in the ...

Researchers have discovered that single-phase CT scans along with clinical data can achieve accuracy equivalent to dual-phase ...

Study shows muscle-to-fat ratio impacts lung function and airflow obstruction risk in adults, emphasising the importance of ...

COPD and preserved ratio impaired spirometry (PRISm) have been identified as key accelerators of frailty progression ... PRISm findings, a newer phenotype characterized by impaired lung function ...

Initial spirometry showed marked obstructive ventilatory disorder, with reduced FVC (pre-BD FEV1: 0.61 (23.9%), post-BD FEV1: 0.61 (23.9%), pre-BD FVC: 1.10 (37.4%), post-BD FVC: 1.05 (35.6%), pre-BD ...

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Other lung volumes are normal. FER: Forced expiratory ratio; FEV 1: Forced expiratory volume in 1 s; FRC: Functional residual capacity; FVC: Forced vital capacity; KCO: Carbon monoxide diffusion ...

We modeled FEV1 and FVC as secondary outcomes to evaluate the association between pulmonary function ... It may be that monitoring dd-cfDNA over time is more sensitive than spirometry in identifying ...

The trial also successfully demonstrated a dose-dependent response. The rate of FVC decline 3 at week 26 with: The trial also achieved its key secondary endpoint based on a prespecified Bayesian ...

PFTs were performed on all patients in a dedicated laboratory, consisting of either standard spirometry or body plethysmography in cases with FVC loss suspected of having restrictive ventilatory ...