Flick MJ et al. (2007) Fibrin(ogen) exacerbates inflammatory joint disease through a mechanism linked to the integrin αMβ2 binding motif. J Clin Invest 117: 3224–3235 Thrombin mediates fibrin ...
which cleaves the fibrin cross-links causing thrombus breakdown. Fibrinolytic therapy is used in the treatment of a ST segment elevation myocardial infarction (STEMI), acute stroke and other less ...
Table 1. Summary of nanoparticulate contrast agents targeting cell adhesion molecules, apoptosis, plaque angiogenesis and thrombosis (platelet activation/aggregation and fibrin targeting).
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