Studies of living participants and postmortem brains confirm that gene expansion is a promising target for HD prevention ...

Scientists have discovered that the protein machines that shape our DNA can switch direction. Until now, researchers believed that these so-called SMC motors that make loops into DNA could move in one ...

New genetic research shows why some people develop deadly Huntington's disease earlier than others. The findings could lead ...

Your body is a collection of cells carrying thousands of genetic mistakes accrued over a lifetime—many harmless, some bad and ...

Scientists have discovered a surprising mechanism by which the inherited genetic mutation known to cause Huntington's disease leads to the death of brain cells. The findings change the understanding ...

New research shows that the mutation is, surprisingly, harmless for decades. But it quietly grows into a larger mutation — ...

Bone pain. Joint pain. Bone swelling. These are symptoms that about 1,000 people in the United States begin to feel each year ...

Information on tumor mutational status was limited before the development of NGS because traditional Sanger sequencing and ...

Approximately 23 years before a clinical diagnosis, CSF analysis showed very early signs of neurodegeneration with elevated ...

The American scholar Lawrence Keeley emphasised a “neo-Rousseauan” strain in archaeological thinking after World War II that ...

One type of co-excluder bacteria, called Faecalibacterium, stood out as particularly important. It produces chemicals called short-chain fatty acids by breaking down a variety of fibres in our diet.