Glucokinase activation patterns the Ca 2+ wave axis, which originates from stochastic β-cell subpopulations on the islet periphery that change between oscillations. • The stochasticity of ‘leader’ ...

By contrast, highly connected or hub cells are stable, and located toward the islet center. Suggesting that the two subpopulations are differentially regulated by fuel input, glucokinase activation ...

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A model showing how metallic bonds are formed - the first diagram shows the outer electrons in their atoms, and the second diagram shows that the electrons have become delocalised ...

Background: This study aimed to analyze the changing trend of diabetes drugs clinical trials in China during 2013-2023, and provided a reference for the research and development of diabetes drugs.