Testosterone helps release growth hormones, which stimulate tissue growth, and it connects with nuclear receptors in DNA, which causes protein synthesis (or muscle growth). Turner points out that ...

Lipid metabolism in homozygous familial hypercholesterolemia (HoFH) is abnormal owing to lack of functional LDL receptors, although residual receptor function between 2 and 25% is present in the ...

Inhibition of PCSK9 at the mRNA or protein levels is an efficacious strategy to lower LDL by increasing the density of LDL receptors on the hepatocyte surface. Evolocumab reduces plasma ApoB and ...