Precision Pharmacy and Drug Development Center, Department of Pharmacy, Tangdu Hospital, Air Force Medical University, Xi’an, Shaanxi, China Introduction: Hepatocellular carcinoma (HCC), the third ...

Most of us remember two things from high school biology: that mitochondria are the powerhouses of cells and that we inherit stable sets of chromosomes from our two parents. Both truisms are only ...

The HDAC family contains 18 members, and depending on the specificity, HDAC inhibitors can demonstrate antitumour property, and boost ICB therapy efficacy in several tested tumour types including ...

Mitochondria are cytoplasmic organelles found in most eukaryotic cells. They are formed from an outer membrane, a highly invaginated inner membrane containing cristae, and a matrix. Mitochondria ...

Hepatocellular carcinoma (HCC) represents the most prevalent form of primary liver cancer and has a high mortality rate. Caspase-8 plays a pivotal role in an array of cellular signaling pathways and ...

In contrast to PTEN knockdown, overexpression of PTEN led to a significant decrease in NADPH levels (data not shown). We also investigated the bioenergetic state of mitochondria in PTEN−/− and PTEN ...

What is the share price of Hindustan Construction Company Ltd (HCC) today on NSE? As on Jan 02, 2025, Hindustan Construction Company Ltd (HCC)’s share price on NSE is Rs 40.37 What is the market ...

Mission Statement: Evidence-based Complementary and Alternative Medicine (eCAM) is an international, peer-reviewed journal that seeks to understand the sources and to encourage rigorous research ...

LEAP-012 is a phase 3, double-blinded, active-controlled, multicenter, randomized trial which sought to evaluate lenvatinib (Lenvima) given with pembrolizumab (Keytruda) and transarterial ...

A team of researchers has now been able to show in mice that adaptations in the liver mitochondria take place ... hepatocellular carcinoma (HCC) is one of the main causes of cancer-related deaths.

At this point, we knew that the way that hyperglycemia activates the four major pathways of hyperglycemic damage is by the overproduction of superoxide by the mitochondria, which then decreases ...