The sNDA is supported by data from the phase 3 ENERGIZE and ENERGIZE-T studies, which evaluated mitapivat vs placebo in patients with NTD and TD alpha- or beta-thalassemia, respectively.
Anemia Deficiency in the concentration of erythrocytes and/or hemoglobin concentration; further defined as a hematocrit or hemoglobin greater than 2 standard deviations below the mean for age and ...
Anemia Deficiency in the concentration of erythrocytes and/or hemoglobin concentration; further defined as a hematocrit or hemoglobin greater than 2 standard deviations below the mean for age and ...
Since the organic phosphate compounds, ATP (adenosine triphosphate) and 2,3-DPG (2,3-diphosphoglycerate), facilitate the release of oxygen from hemoglobin, the concentration of these compounds in ...
The blood test can be helpful in diagnosing anemia. Mean corpuscular hemoglobin concentration (MCHC) is a measurement of the amount of hemoglobin a red blood cell has relative to the cell's volume.
The plasma hemoglobin concentration at the end of walks of 1 to 3 miles was between 32 and 64 mg. per 100 cc. (Table 1). Walks that occasioned plasma hemoglobin levels of approximately 50 mg.
Anemia significantly impacts global public health, with over 571 million women at risk of adverse health outcomes due to iron deficiency and other causes.