The top-line results of DESTINY Breast-04 are impressive - in patients with HER2-low metastatic breast cancer who received multiple lines of prior treatment, Enhertu (trastuzumab deruxtecan ...
HER2-negative breast cancers are HER2-low and potentially an additional 25% may be HER2-ultra-low. There are no targeted therapies specifically approved for patients with HER2-ultra-low expression ...
Background: Variable rates of HER2 protein overexpression and gene amplification have been reported in advanced ovarian cancers (AOC). Trastuzumab, tested only as a single agent, has been shown to ...
NEW YORK – Eli Lilly on Monday said it will acquire Scorpion Therapeutics' mutant-PI3Kα inhibitor STX-478 for up to $2.5 billion while Scorpion spins out a new entity to develop its non-PI3Kα assets.
Medscape Medical News, December 19, 2024 SABCS 2024 T-DXd Effective in HR+/HER2-Low BC After Endocrine Failure New DESTINY-Breast06 analysis showed trastuzumab deruxtecan doubled PFS versus ...