Researchers unveil histone-based age predictors, offering a new window into epigenetic aging and its shared patterns across ...

This enzyme is able to silence specific DNA sections by epigenetically modifying histone proteins that package the DNA. These ...

How? Scientists are using ChIP and PCR to find out. To examine changes in histone modification during blood cell development in chickens, the investigators started with whole chromatin from ...

Histone deacetylation and other modifications, particularly the methylation of lysine 9 within histone H3 (H3-K9) residues located in the histone tails, cause chromatin condensation and block ...

While each cell contains the complete genetic blueprint of an organism, chemical marks on the DNA – so-called epigenetic ...

Epigenetic changes, including histone modifications and proteome, are critical regulatory mechanisms, involved in all developmental processes including aging and age-associated diseases. The goal of ...

Setd2 is instrumental in the trimethylation of histone H3 lysine 36 (H3K36me3), a modification that influences gene expression and has been implicated in various cancers and developmental disorders.

Epigenetic regulation relies on the dynamic modification of the two building blocks of chromatin: DNA and histone packaging proteins, to establish and maintain cell identity and fate. We develop and ...

SETD2 is the only enzyme responsible for transcription-coupled histone H3 lysine 36 trimethylation (H3K36me3). Mutations in ...

This enzyme is able to silence specific DNA sections by epigenetically modifying histone proteins that package the DNA. These modifications ensure that the DNA is densely packed as heterochromatin ...

This enzyme is able to silence specific DNA sections by epigenetically modifying histone proteins that package the DNA. These modifications ensure that the DNA is densely packed as heterochromatin ...