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This study identifies a novel immune checkpoint in senescent cells that is linked to the ganglioside GD3 and that contributes to the evasion of immune clearance by these cells and to aging and age ...

A recent multicentre study has highlighted the potential of venetoclax combined with decitabine as an effective first-line treatment for older patients with acute myeloid leukaemia (AML) who are ...

In the final episode, experts at UCSD and La Jolla Institute discuss current clinical trials of a cancer vaccine and future directions for neoantigen vaccines. Custom-made Cancer Therapy ...

Evidence for the effects of sex hormones on inflammation, myelination and neurodegeneration has implications for both cisgender and gender-diverse individuals with multiple sclerosis. Here, the ...