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Lanosterol 14α-Demethylase (CYP51)/Heat Shock Protein 90 (Hsp90) Dual Inhibitors for the ...
The Center for Basic Research and Innovation of Medicine and Pharmacy (MOE), School of Pharmacy, Second Military Medical University (Naval Medical University), 325 Guohe Road, Shanghai 200433, China ...
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【科技前沿】Nat Commun｜中国科大黄成栋团队揭示Hsp90动态机制的原子 ...
2024年12月11日，中国科学技术大学生命科学与医学部黄成栋教授团队在 Nature Communications 期刊发表了题为“The Dynamic Triage Interplay of Hsp90 with its Chaperone Cycle and Client Binding”的研究论文。该研究利用液体核磁共振（NMR）技术，首次在原子分辨率上解析了Hsp90在ATP循环 ...