Laboratory of Inorganic Materials and Catalysis, Department of Chemical Engineering and Chemistry, Eindhoven University of Technology, P.O. Box 513, 5600 MB Eindhoven, The Netherlands ...
Enzyme mechanisms are the chemical transformations, and the steps within them, generated by enzymatic action on substrates. The mechanism of enzyme catalysis is similar in principle to other types ...
Here, the authors use a molecular dynamics guided reaction discovery approach and identify endoperoxide-to-alkoxy isomerization as a key branching point in the mechanism. The synthesis of ...