Immune tolerance — the adaptation of the immune system to external antigens or allergens — might be therapeutically manipulated to restore normal immunity in conditions such as allergy ...

Researchers have uncovered a hierarchical structure of immune-privileged stem cells in bone marrow niches, revealing their ...

Epitope-specific immunotherapy is based on the principle of reducing the reactivity of the adaptive immune system to proinflammatory epitopes by inducing immune tolerization. A pilot phase II ...

Building on 7 years of success, the 8th Antigen-Specific Immune Tolerance Summit is back - the only conference dedicated to advancing curative therapies for autoimmune diseases through antigen ...

Metabolites—small molecules within cells, biofluids, tissues or organisms—play an integral role in various diseases, and ...

Tregs are essential for maintaining immune tolerance and preventing inflammatory diseases. However, the regulatory mechanisms of Aldh1a2 expression and Raldh2 function remain unclear ...

PHILADELPHIA, PA — Tolerance Bio, Inc. has announced the completion of a $20.2 million seed financing round and the formation ...

Barinthus Biotherapeutics (BRNS) provided a strategic business and financial update. Barinthus Bio is a clinical-stage biopharmaceutical ...

Research reveals how the dietary flavonoid promotes regulatory T cell development and suppresses inflammation through key immune pathways. Study: Kaempferol Exerts Anti-Inflammatory Effects by ...

antigen presentation; gene regulation and recombination; cellular and systemic immunity; vaccines; immune tolerance; autoimmunity and tumor immunology, microbial immunopathology; and transplantation.

Prioritizing VTP-1000 development in celiac disease, Phase 1 data expected in mid-2025Postponing further clinical development of VTP-300 in ...

We also found that tumor growth induces overly activated regulatory T (Treg) cells with their CTL suppressor function titratable along the PI3K-Akt-Foxo1 signaling pathway to overcome cancer immune ...