The emergence of induced pluripotent stem cell (iPSC) technology has had a great impact on the field of medicine ever since the ground-breaking discovery in 2006 that overexpression of four specific ...

Stem cells can be unipotent, multipotent, pluripotent or totipotent, depending on the number of cell types to which they can give rise. Human induced ... in response to factors such as calorie ...

a critical transcription factor essential for early embryo development. Their findings enhance our understanding ... New Drug Tested to Reduce Side Effect of 'Half-Matched' Stem Cell Transplants Dec.

Cell reprogramming is the process of reverting mature, specialised cells into induced pluripotent stem cells ... signalling by promoting plasticity factors and that this signalling outside ...

Cover picture: Inspired by the Review by Jung-Soon Mo, Hyun Woo Park and Kun-Liang Guan. Illustrated by Sandra Krahl.

New Cambridge, Massachusetts biotech GC Therapeutics has launched with $65 million in first-round funding for its 'plug-and-play' cell therapy platform, which uses induced pluripotent stem cells ...

Transcription is a fundamental cellular process, and the first step of gene expression. In human cells, it depends on the binding to chromatin of various proteins, including RNA polymerases and ...

In response to exercise, the heart rate speeds up, and blood vessels within tissues narrow (vasoconstriction). Exercise-induced vasoconstriction is triggered by the release of adrenaline, a hormone ...

Our data suggest that EBNALP regulates YY1 to rewire the host genome, which might facilitate naive B-cell transformation. EBNALP alters looping factor YY1 DNA binding and 3D genome organization which ...