Here, in bone marrow transplantation and organoid culture models, T-cell-derived Interferon-γ is shown to promote STAT1-dependent intestinal stem cell c-MYC expression and epithelial regeneration.

Histological analyses of the small intestine in C57BL/6 mice treated with 200[μg/ml NIC (which emulates active smoking) revealed that NIC exposure decreased villus length without affecting crypt size ...

Correspondence to Dr Sebastian Zeissig, Department of Medicine I, University Medical Center Dresden, and Center for Regenerative Therapies Dresden (CRTD), Technische Universität (TU) Dresden, 01307 ...

The effects of signalling pathway modulators on the status of intestinal stem cell biology, crypt cell proliferation, migration, differentiation and shedding were determined. Results Native human ...

To study these cells, the researchers studied mice infected with parasites and viruses on various feeding schedules. They then measured changes in tuft cells and various signals.

Dec. 18, 2024 — Scientists have generated human stem cell models which contain notochord -- a tissue in the developing embryo that acts like a navigation system, directing cells where to build ...

The study shows for the first time the capacity of these particles to be absorbed by human intestinal cells, and are thus able to reach the bloodstream and spread throughout the body. Plastic ...

Jan. 3, 2025 — Biologists have shown that the surfaces of plant leaves are coated with a diverse array of RNA molecules. The finding suggests that the RNA present ...

Dr. Gary Luker's study shows that breast cancer can lie dormant for years after treatment, especially in patients on estrogen therapy. The study can help pave way for better cancer treatments. Breast ...