It is accomplished by stem cells that originate in intestinal crypts—microscopic depressions in the intestinal wall. In stark ...

displaying typical ‘budding crypts’ and a central ‘villus-like’ domain. The main intestinal cell types are shown in green, blue, red and purple. Membranes are yellow and nuclei cyan.

Others suggest there's a dormant population of stem ... cell RNA sequencing to characterize all the cells in the crypts, the region of the intestine where the stem cells are known to reside ...

Here, in bone marrow transplantation and organoid culture models, T-cell-derived Interferon-γ is shown to promote STAT1-dependent intestinal stem cell c-MYC expression and epithelial regeneration.

and bond formation to study how intestinal stem cell colonies respond to alterations in geometric confinement, mirroring processes observed in vivo. Looking ahead, we seek to identify unique ...

I don't necessarily think about normal stem cells dying when colon cancer is starting,” Sethi commented. To understand the sequence of these early events, the researchers did a timed deletion of one ...

Intestinal stem cell-specific TLR4 expression affects the proliferation and apoptosis rate in the intestinal crypt. In addition, stem cell lineage commitment is also influenced by stem cell ...